Trials / Completed
CompletedNCT02897206
Imipenem Prophylaxis in Patients With Acute Pancreatitis
Imipenem Prophylaxis of Infectious Complications in Patients With Acute Pancreatitis
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 98 (actual)
- Sponsor
- University Hospital Rijeka · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a prospective, single-center, randomized, placebo-controlled, double-blind clinical trial that aims to investigate the beneficial and harmful effects of prophylactic use of imipenem in patients with predicted severe acute pancreatitis. All patients with first attack of acute pancreatitis, an onset of disease less than 72h before admission, and an APACHE II score ≥ 8 calculated within the first 24h from admission will be enrolled.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Imipenem | A wide-spectre antibiotic from the carbapenem group |
| DRUG | Placebo | An imipenem-matching placebo |
Timeline
- Start date
- 2014-10-01
- Primary completion
- 2016-12-01
- Completion
- 2016-12-01
- First posted
- 2016-09-13
- Last updated
- 2017-06-20
Locations
1 site across 1 country: Croatia
Source: ClinicalTrials.gov record NCT02897206. Inclusion in this directory is not an endorsement.