NCT02894229

The Stress Reduction Intervention Study

The Mindfulness Intervention and Repeated Acute Stress (MIRAS) Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Ohio University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The primary purpose of the present study is to investigate the relationship between mindfulness and stress habituation. The investigators propose to measure the effect of mindfulness on stress habituation by randomly assigning participants to a 6-week mindfulness-based stress reduction group intervention, a cognitive-behavioral skills group comparison intervention, or a waitlist control condition followed by repeated acute psychosocial stress testing (2 laboratory sessions on 2 separate days). Saliva will be collected from participants throughout both laboratory testing sessions to measure HPA axis activation (an essential stress-responsive system), along with other measures of physiological and psychological stress (e.g., heart rate, blood pressure, emotions). Mediators and moderators of treatment outcome will be examined. The cognitive-behavioral skills group condition is an appropriate comparison group due to the well-documented efficacy of cognitive-behavioral interventions on stress.

Conditions

• Stress, Physiological
• Stress, Psychological

Interventions

Type	Name	Description
BEHAVIORAL	Mindfulness Based Stress Reduction	A modified version of traditional MBSR. The current study's version of MBSR is shortened to 6-weeks.
BEHAVIORAL	Cognitive-Behavioral Therapy (CBT) Group	A 6-week, 2-hour per group, skills group that focuses on various cognitive-behavioral skills for stress reduction (e.g., progressive muscle relaxation; cognitive restructuring).

Timeline

• Start date: 2016-08-01
• Primary completion: 2019-07-01
• Completion: 2019-07-01
• First posted: 2016-09-09
• Last updated: 2018-04-04