NCT02892981

Dead Space Evaluation in Pulmonary Hypertension

Dead Space Evaluation During Exercise in Patients With Pulmonary Hypertension

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Centro Cardiologico Monzino · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Aim of the study is to evaluate the role of chemoreceptor activity and ventilation perfusion mismatch on the genesis of exercise induced hyperventilation in Pulmonary hypertension patients. So the investigators tested the chemoreceptor response at rest, both with hypoxic and hypercapnic stimuli, and the ventilatory response during exercise analyzing its two components, alveolar and dead space ventilation.

Conditions

• Pulmonary Hypertension

Interventions

Type	Name	Description
OTHER	cardiopulmonary exercise test,hypoxia and hypercapnia test	class I and IV Pulmonary hypertension patients in stable haemodynamic status and optimized medical therapy underwent cardiopulmonary test and hypoxia and hypercapnia tests to evaluate the chemoreceptor sensitivity

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-01-01
• Completion: 2016-04-01
• First posted: 2016-09-08
• Last updated: 2016-09-08