Clinical Trials Directory

Trials / Completed

CompletedNCT02892045

Mindray Neuromuscular Transmission Transducer

Sensitivity and Specificity of the New Mindray 3-Directional Neuromuscular Transmission Module Versus the Relaxometer Mechanomyograph and Versus TOF-Watch Acceleromyograph for Neuromuscular Block Monitoring

Status
Completed
Phase
Study type
Observational
Enrollment
48 (actual)
Sponsor
Suez Canal University · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

A new NMT module from Mindray (Mindray Co. Shenzhen, People's Republic of China.) claims to measure 3 directional accelerography. The aim of the study is to compare the neuromuscular block of rocuronium 0.6 mg/kg (twice the 95% effective dose, ED95) monitored by the NMT versus that monitored by the Relaxometer Mechanomyograph on the other hand in Group 1, and versus the TOF-Watch on the other hand in Group 2 to clinically evaluate the new system for its diagnostic accuracy.

Detailed description

Mechanomyography (MMG) is regarded as the standard method for precise quantification of neuromuscular block. The conventional MMG measures the exact force of muscle contraction in response to electric stimulation of the ulnar nerve. MMG quantifies the neuromuscular function by measurement of the force displacement. However the equipment is rather bulky, takes time to set up, requires a rigid support of the arm in an often-crowded operating room. This limits its clinical use in the daily anesthesia practice. Acceleromyography is based on the acceleration of a piezo-electrode. A new NMT module from (Shenzhen, People's Republic of China.) claims to measure 3 directional accelerography. The aim of the study is to compare the neuromuscular block of rocuronium 0.6 mg/kg (twice the 95% effective dose, ED95) monitored by the NMT to that monitored by the Relaxometer Mechanomyograph in Group 1, and versus TOF-Watch Acceleromyograph in Group 2 to clinically evaluate the new system for its diagnostic accuracy.

Conditions

Interventions

TypeNameDescription
DEVICEMMGneuromuscular monitoring device

Timeline

Start date
2016-09-01
Primary completion
2017-09-01
Completion
2017-09-01
First posted
2016-09-08
Last updated
2019-06-24

Locations

2 sites across 2 countries: Bosnia and Herzegovina, China

Source: ClinicalTrials.gov record NCT02892045. Inclusion in this directory is not an endorsement.