NCT02885935

Dairy Macronutrient Effects on the Metabolic Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 45 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The investigators examined the effects of 4-week dietary protein intake in mixed meals at two levels of protein amount on whole body glucose metabolisms in older adults with metabolic syndrome.

Detailed description

The investigators investigated changes in insulin sensitivity before and after 4 weeks of dietary intervention and control in subjects with metabolic syndrome. Two groups of subjects were studied before and after a weight maintenance diet. Group 1 was fed a common American diet with a macronutrient distribution of 10% protein, 55% carbohydrates, and 35% fat. Group 2 consumed a higher protein diet (20%; 1.4 g/kg/d of protein). Carbohydrate intake was lower in Group 2 (45%), with fat intake (largely derived from dairy sources) similar between groups. Glucose utilization and endogenous glucose production were determined during an oral glucose tolerance test (OGTT) with a novel double-tracer approach. The secondary aim was to determine the effect of a diet high in dairy consumption on blood lipid profiles. The investigators measured blood lipids before and after dietary intervention in each group.

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
OTHER	Recommended protein intake	Recommended protein intake diet contained 10% protein, 55% carbohydrate,and 35 % fat.
OTHER	Elevated protein intake	Recommended protein intake diet contained 20% protein, 45% carbohydrate,and 35 % fat.

Timeline

• Start date: 2013-04-01
• Primary completion: 2014-09-01
• Completion: 2014-09-01
• First posted: 2016-09-01
• Last updated: 2016-09-01