Trials / Completed
CompletedNCT02885038
Effect of Product Related Factors on Platelet Concentrate Transfusion Response in Patients With Hematologic Malignacies
Analyse de l'Effet Des caractéristiques de concentrés Plaquettaires Sur le Rendement Transfusionnel Chez Les Patients Ayant Une hémopathie Maligne et bénéficiant de Transfusions Plaquettaires à Titre Prophylactique
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,101 (actual)
- Sponsor
- Etablissement Français du Sang · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Platelet concentrates (PCs) characteristics, such as storage duration, ABO compatibility, dose and source, may have an impact on transfusion responses and outcomes. Because of the relative scarcity of PCs the selection of a specific PC for issue to the patient remains a challenging process. Regulatory agencies do not fully address these characteristics in their recommendations for prophylactic transfusions. The aim of the study was to analyse the effect of product-related factors in a real life setting, in order to determine which ones are the most relevant when selecting PCs for patients in prophylactic conditions. Two different endpoints are studied: the corrected count increment and the platelet transfusion time intervals.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Platelet concentrate transfusion |
Timeline
- Start date
- 2015-01-01
- Primary completion
- 2016-03-01
- Completion
- 2016-03-01
- First posted
- 2016-08-31
- Last updated
- 2017-10-02
Source: ClinicalTrials.gov record NCT02885038. Inclusion in this directory is not an endorsement.