NCT02880787

Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 142 (estimated)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

The purpose is to evaluate the reproducibility of neuromuscular monitoring data of recovery from neuromuscular blockade, obtained with TOFScan® and TOF-Watch SX®, in adult and pediatric population. Secondary purposes are to evaluate the reproducibility of data obtained with 2 monitors for: * the onset of clinical action of curare: suppression of the first response of train of four monitoring (T1) of 95% initial value * the duration of clinical action of curare: recovery of the first response of train of four monitoring (T1) to 25% initial value * recovery of first (T1), second (T2), third (T3) and fourth response (T4) of train of four monitoring, and recovery of T4/T1 to 40% and 60% initial value (T4/T1 0.4 and 0.6) * complete recovery from curarisation, at T4/T1=90% and T4/T1=100%.

Conditions

• Curarisation
• Neuromuscular Monitoring

Interventions

Type	Name	Description
DRUG	Rocuronium	Anesthesia induction with Propofol and maintaining with desflurane. For adult patients, the curare is rocuronium (0.6 mg/kg) For pediatric patients, the curare can be rocuronium (0.6 mg/kg), cisatracurium (0.1 mg/kg) or atracurium (0.5 mg/kg)
DEVICE	Neuromuscular monitoring with TOFScan® and TOF-Watch SX®	Each monitor on one arm

Timeline

• Start date: 2014-11-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2016-08-26
• Last updated: 2016-08-26

Locations

1 site across 1 country: France