Clinical Trials Directory

Trials / Completed

CompletedNCT02879630

Prospective Evaluation of Adjusted Body Weight Dosing of Acyclovir in Obesity

Status
Completed
Phase
Study type
Observational
Enrollment
13 (actual)
Sponsor
West Virginia University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Patients receiving acyclovir as standard of care will be enrolled into this study. The currently recommended dosing strategy at our institution for obese patients is to receive intravenous acyclovir dosed per an adjusted body weight \[IBW + 0.4(TBW-IBW)\]. They will have blood drawn once prior to the first dose of acyclovir and 10 times thereafter, over a total time period of 12 hours. These patients will already be hospitalized for other reasons, and will not be required to make additional trips to the hospital. A total of approximately 4-5 tablespoons of blood will be drawn for this study. Ten obese patients and 10 matched control (non-obese) patients will be enrolled.

Conditions

Timeline

Start date
2016-11-28
Primary completion
2026-02-16
Completion
2026-02-16
First posted
2016-08-25
Last updated
2026-04-16

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02879630. Inclusion in this directory is not an endorsement.