NCT02878954

Exercise in Peripheral Artery Disease

Exercise in Peripheral Artery Disease - Gender-specific Differences and Unexplored Opportunities in Women: the GrEnADa-project

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: KU Leuven · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This research project aims to investigate the gender-based difference in patients with peripheral artery disease. To attend this, this study has two specific objectives: Objective 1: To identify gender-specific barriers towards exercise and physical activity in patients with peripheral artery disease (PAD). Objective 2: To evaluate gender-specific differences in functional capacity and cardiovascular function and regulation in patients with PAD at rest, during and following a single session of maximal exercise.

Conditions

• Peripheral Artery Disease
• Intermittent Claudication

Interventions

Type	Name	Description
OTHER	No intervention (Observational study)	160 patients will be recruited to: * Fill in questionnaires related to demographic characteristics, severity of disease and physical activity. * Perform a six-minute walk test Comparison between men and women will be performed.
OTHER	Control session	Out of the 160 participants of the observational study, at least 40 (20 men and 20 women) will be recruited. In the control session participants will be seated in resting position for 15 minutes.
OTHER	Exercise session	40 patients will perform a single maximal exercise test on a treadmill. Speed will be maintained at 3.2 km/h and the grade will be increased with 2% every 2 min following Gardner's protocol.

Timeline

• Start date: 2017-01-01
• Primary completion: 2019-09-01
• Completion: 2019-12-01
• First posted: 2016-08-25
• Last updated: 2016-08-25