Trials / Completed
CompletedNCT02877628
Immunosuppressive Therapy Optimization: Development of a Population Pharmacokinetic-pharmacodynamic (PK-PD) Model in Liver Transplantation
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 110 (actual)
- Sponsor
- Rennes University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Prospective, non-randomized, open Pharmacokinetic-Pharmacogenetic-Pharmacodynamic monocentric study. Donor and recipient CYP3A5 genotype and recipient ABCB1 will not be communicate to clinicians or patients during the study.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Pharmacokinetic-pharmacodynamic model in liver transplantation | Biological: tacrolimus and calcineurin dosage, donor and recipient CYP3A5 and ABCB1 genotypes determination |
Timeline
- Start date
- 2015-10-31
- Primary completion
- 2018-11-29
- Completion
- 2018-12-01
- First posted
- 2016-08-24
- Last updated
- 2019-01-28
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02877628. Inclusion in this directory is not an endorsement.