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Trials / Completed

CompletedNCT02877186

Effects of Non-nutritive Sweeteners on the Composition of the Gut Microbiome

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
22 (actual)
Sponsor
George Washington University · Academic / Other
Sex
All
Age
18 Years – 35 Years
Healthy volunteers
Accepted

Summary

This pilot study is being conducted to evaluate whether consumption of diet soda sweetened with sucralose and acesulfame-potassium leads to changes in the gut microbiota. Following a one week run-in period, healthy, young adults are randomized to consume either diet soda or carbonated water (control) three times per day for one week. Stool and urine samples are collected at baseline, following the run-in, and after the one-week intervention.

Conditions

Interventions

TypeNameDescription
OTHERcommercially-available diet sodaSubjects are asked to consume diet soda three times daily for one week.
OTHERcarbonated water (control)Subjects are asked to consume carbonated water three times daily for one week.

Timeline

Start date
2015-02-01
Primary completion
2019-12-01
Completion
2019-12-01
First posted
2016-08-24
Last updated
2020-08-20

Source: ClinicalTrials.gov record NCT02877186. Inclusion in this directory is not an endorsement.

Effects of Non-nutritive Sweeteners on the Composition of the Gut Microbiome (NCT02877186) · Clinical Trials Directory