NCT02875704

Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 77 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

In this study, markers of oxidative stress will be measured in the aqueous humour of stargardt disease, age related macular degeneration and diabetic retinopathy patients compared to controls.

Detailed description

People with Stargardt disease, age related macular degeneration (AMD) and diabetic retinopathy (DR) have decrease in central vision from damage to photoreceptors. One of the mechanisms causing damage is high levels of oxygen in the eye. This damage produces specific biomarkers that can be measured in eye fluid (aqueous humor). In this study, these biomarkers will be assessed in people with Stargardt disease, age related macular degeneration and diabetic retinopathy, compared to controls.

Conditions

• Stargardt Disease
• Diabetic Retinopathy
• Macular Degeneration (Age Related)

Interventions

Type	Name	Description
OTHER	Anterior Chamber (AC) Tap	Aqueous Samples will be collected for measurement of biomarkers

Timeline

• Start date: 2017-01-03
• Primary completion: 2022-06-06
• Completion: 2022-09-22
• First posted: 2016-08-23
• Last updated: 2022-09-26

Locations

1 site across 1 country: United States