Clinical Trials Directory

Trials / Terminated

TerminatedNCT02872649

Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device (LVAD)

Pilot-Trial: Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Daniel Zimpfer, MD · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Patients with severe heart failure supported by left ventricular assist device (LVAD) require adequate long-term anticoagulant therapy. New oral anticoagulants such as the direct thrombin inhibitor dabigatran may represent an alternative to Coumarin for long-term anticoagulation. In this pilot single-center study, thirty LVAD patients with stable renal function were scheduled to receive phenprocoumon or dabigatran for long-term anticoagulation after implantation of a HeartWare HVAD system following an open-label balanced parallel group design.

Conditions

Interventions

TypeNameDescription
DRUGDabigatran
DRUGPhenprocoumon

Timeline

Start date
2013-01-01
Primary completion
2015-06-01
Completion
2016-02-01
First posted
2016-08-19
Last updated
2016-08-19

Locations

1 site across 1 country: Austria

Source: ClinicalTrials.gov record NCT02872649. Inclusion in this directory is not an endorsement.