NCT02871960

Surgical Stress and Colorectal Surgery

Evaluation of Surgical Stress and Immune Response After Minimally Invasive Colorectal Surgery (ESSIMIC)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 170 (actual)
• Sponsor: Federico II University · Academic / Other
• Sex: All
• Age: 50 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate surgical stress and immune function after robotic versus laparoscopic colectomy.

Detailed description

The short-term advantages of minimally invasive colon resection have been well established in several randomized trials. A major factor in the development of morbidity is the surgical stress response with subsequent increased demand on the patient's reserves and immune competence. Although the advantage in term of stress response of laparoscopic surgery over open surgery has been widely reported, little is known about the role of robotic surgery. Robotic approaches have seen significant growth in the last 5 years. Taking advantage of three-dimensional visualization, improved articulation, and multiple operating arms provides theoretical advantages in colorectal cancer surgery. In an attempt to evaluate the surgical stress response and immune function after robotic colorectal surgery a comparative study has been designed. Two surgical procedures were evaluated: Robotic colorectal resection (Experimental group) and Laparoscopic colorectal resection (Control group).

Conditions

• Surgical Stress and Immune Function

Interventions

Type	Name	Description
PROCEDURE	Robotic and Laparoscopic Colectomy

Timeline

• Start date: 2016-01-01
• Primary completion: 2020-08-01
• Completion: 2020-11-01
• First posted: 2016-08-18
• Last updated: 2020-01-22