Clinical Trials Directory

Trials / Unknown

UnknownNCT02871466

Stem Cells Therapy in Advanced Heart Failure

Intra Cardiac Autologous Stem Cells Infusion May Improve Clinical Outcomes in Failing Heart Subjects Refractory to Maximal Drug Therapy and Internal Cardioverter With a Defibrillator (ICD) Recipients

Status
Unknown
Phase
Phase 4
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
University of Campania Luigi Vanvitelli · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

stem cells therapy may be a choice therapy for advanced heart failure patients refractory to medical therapy, internal cardiovertor with a defibrillator (ICD) recipients, and a previous history of myocardial infarction and coronary artery revascularization. These patients, without indication to receive a cardiac resynchronization therapy (CRT), may have a worsening of heart failure, and symptoms of coronary artery disease. In this study we have evaluated in consecutive 30 selected patients the amelioration in failing heart NYHA class, hospitalization rate, echocardiographic left ventricle functionality, and associated to reduction of angina after a treatment with stem cells intra thoracic infusion.

Conditions

Interventions

TypeNameDescription
DRUGstem cells infusion

Timeline

Start date
2010-01-01
Primary completion
2022-01-01
Completion
2022-07-01
First posted
2016-08-18
Last updated
2020-08-13

Locations

3 sites across 1 country: Italy

Source: ClinicalTrials.gov record NCT02871466. Inclusion in this directory is not an endorsement.