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UnknownNCT02869984

Clinical Trial Assessing 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Anterior Resection Syndrome

Status
Unknown
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
100 (estimated)
Sponsor
Seoul National University Hospital · Academic / Other
Sex
Male
Age
19 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Poor functional outcomes has been reported inevitably, and up to 90% of the patients have experienced bowel habit changes after sphincter-saving surgery for rectal cancer. But, currently there has been no specific treatment for ARS and symptom based empirical management is tried Recently, 5-HT3 receptor antagonists can be used for treatment of IBS-D, and has been revealed to be slowing the bowel movement and improving stool consistency and urgency. We performed the clinical trial with using ramosetron (Irribow®) for the treatment of ARS

Conditions

Interventions

TypeNameDescription
DRUGRamosetron

Timeline

Start date
2016-08-01
Primary completion
2018-10-01
First posted
2016-08-17
Last updated
2016-08-17

Source: ClinicalTrials.gov record NCT02869984. Inclusion in this directory is not an endorsement.

Clinical Trial Assessing 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Anterior Resection Syndrome (NCT02869984) · Clinical Trials Directory