NCT02869841

Efficacy of Rectal Sheath Analgesia After Midline Laparotomy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 57 (actual)
• Sponsor: Kuopio University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Midline laparotomy is commonly used in emergency and elective cancer surgery and patients need effective and safe pain treatment after this type of surgery. Nowadays modern anticoagulant therapy may prevent use of central regional blocks in pain management. Therefore in the present study the efficacy and safety of rectus sheath analgesia is studied using different administration techniques. The primary aim is the efficacy of the rectus sheath analgesia measured with pain ratings and the amount rescue opioid used. Secondary aims were concentrations of local anesthetic, rescue opioid and satisfaction to analgesia method used.

Conditions

• Surgery
• Pain Postoperative

Interventions

Type	Name	Description
DRUG	Levobupivacaine continuous infusion	Levobupivacaine continuous infusion to rectus sheath catheters
DRUG	levobupivacaine bolus dosing	Levobupivacaine bolus dosing to rectus sheath catheters
DRUG	single bolus of levobupivacaine	Levobupivacaine single dose to rectus sheath catheters
OTHER	Placebo	No rectus sheath analgesia

Timeline

• Start date: 2012-01-01
• Primary completion: 2018-07-01
• Completion: 2022-12-31
• First posted: 2016-08-17
• Last updated: 2023-10-27

Locations

1 site across 1 country: Finland