NCT02864823

Perichondrium Autograft in Refractory Necrotizing Scleritis

Autologous Perichondrium Transplantation for Replacement of Stem Cells and Their Niche in the Treatment of Necrotizing Scleritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Chung-Ang University Hosptial, Chung-Ang University College of Medicine · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Necrotizing scleritis with severe ischemia is refractory to conventional treatment because of avascular necrosis. The investigators assessed the therapeutic efficacy and safety of autologous perichondrium transplantation in patients with severe ischemic necrotizing scleritis, and analyzed the therapeutic effects.

Detailed description

Ischemic necrotizing scleritis patients who showed persistent and progressive scleral melting were included in this study. Perichondrium tissue was harvested from the patient's ear cartilage and transplanted to reconstruct the scleral defect after the necrotic tissue removal.

Conditions

• Necrotizing Scleritis

Interventions

Type	Name	Description
PROCEDURE	Perichondrium Autografts	Perichondrium tissue was harvested from the patient's ear cartilage and transplanted to reconstruct the scleral defect.

Timeline

• Start date: 2011-03-01
• Primary completion: 2016-06-01
• Completion: 2016-06-01
• First posted: 2016-08-12
• Last updated: 2016-08-12

Locations

1 site across 1 country: South Korea