NCT02862639

Efficacy of Viscosupplementation Associated With Intra-articular Corticosteroid Injection Versus Intra-articular Injection of Corticosteroids Alone in Osteoarthritis of Hip

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: CHU de Reims · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The current management of osteoarthritis is based on non-pharmacological and pharmacological means which include intra-articular injections. The recommendations on the management of hip osteoarthritis stipulate that intra-articular injections of corticosteroid may be considered in patients with an exacerbation not responding to oral treatments. Several recent studies show the effectiveness of intra-articular corticosteroids compared with anesthetics. The intra-articular injection of viscosupplementation alone has never been validated in this indication since controlled studies did not show efficacy over placebo. At present, viscosupplementation is considered an anti-osteoarthritic symptomatic slow-acting and its interest is not yet established in hip osteoarthritis.

Detailed description

Show the superiority of intra-articular injection of viscosupplementation in combination with corticosteroid compared to intra-articular injection of corticosteroid alone in the treatment of hip osteoarthritis.

Conditions

• Hip Osteoarthritis

Interventions

Type	Name	Description
DEVICE	Experimental group	patient receive intra articular injection (hip joint) of viscosupplementation in combination with corticosteroid
DEVICE	control group	patient receive intra articular injection (hip joint) of corticosteroid alone

Timeline

• Start date: 2014-02-01
• Primary completion: 2015-11-01
• Completion: 2015-11-01
• First posted: 2016-08-11
• Last updated: 2017-07-27

Locations

1 site across 1 country: France