NCT02862509

Effectiveness of Budesonide Nasal Instillation in a Vertex-to-floor Position

Effectiveness of Budesonide Nasal Instillation in a Vertex-to-floor Position in Chronic Rhinosinusitis Patients Underwent Endoscopic Frontal Sinus Surgery: a Randomized, Controlled Trial.

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Khon Kaen University · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

o Chronic rhinosinusitis is one of the most common health issue affected American population. Surgery plays an important role in the patients who failed the medical treatment. The most difficult location to be operated endoscopically is the frontal sinus. Frontal sinus is also found to be one of the most common sinus for residual and recurrence after the operation. Intranasal steroid seems to be one of the most beneficent post-sinus surgery cares. The topical therapy can be delivered by many approaches. According to the standard clinical practice guideline and recommendations, intranasal corticosteroid spray is suggested. The technique proved to have greater distribution than standard intranasal spray is instillation of steroid nose drops. The head position for instillation of steroid nose drops proven to have a greater access to olfactory cleft and frontal area is Vertex-to-floor position.

Conditions

• Chronic Frontal Rhinosinusitis
• Vertex to Floor Position

Interventions

Type	Name	Description
DRUG	Budesonide nasal instillation
DRUG	Normal saline nasal instillation

Timeline

• Start date: 2015-11-01
• Primary completion: 2017-08-01
• Completion: 2017-08-01
• First posted: 2016-08-11
• Last updated: 2016-08-19

Locations

2 sites across 1 country: Thailand