NCT02860507

Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency

A Randomized, Blinded-assessor, Single Center Study to Determine if Administration of Sugammadex, When Used to Reverse Deep Neuromuscular Blockade (NMB) After Open Abdominal Surgery, Impacts Hospital Efficiency

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: University of South Florida · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy of Sugammadex in rapidly reversing deep neuromuscular blockaded (induced by rocuronium)

Detailed description

Participants in the study group will receive a single bolus of Sugammadex (4.0mg/kg) prior to extubation. In the post-anesthesia care unit (PACU), a blinded safety-assessor will use the visual analog scale to clinically assess post-operative pain. Post-operative nausea and vomiting (PONV) will be assessed using a PONV rating scale every 30 minutes until PACU discharge. All patients will be monitored with continuous pulse-oximetry.

Conditions

• Neuromuscular Blockade

Interventions

Type	Name	Description
DRUG	sugammadex
DRUG	Neostigmine
DRUG	Glycopyrrolate

Timeline

• Start date: 2016-08-01
• Primary completion: 2018-02-01
• Completion: 2018-02-01
• First posted: 2016-08-09
• Last updated: 2019-04-12
• Results posted: 2019-04-12