Trials / Terminated
TerminatedNCT02857556
Potential Biomarkers of the Severity of Endothelial Damage in End-stage Chronic Kidney Failure
Potential Biomarkers of the Severity of Endothelial Damage in End-stage Chronic Kidney Failure Evaluated at the Initiation of Intermittent or Peritoneal Dialysis
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- Centre Hospitalier Universitaire Dijon · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The principal objective of this study is to qualify markers of oxidative stress in inflammatory cells (monocytes) in patients with stage 3 kidney failure (diabetic or not), and patients with end-stage kidney failure (diabetic or not), who require dialysis. The evaluation of these markers will be done by the activation and localization of proteins implicated in vascular tone and oxidative stress in monocytes, correlated with the distribution of cholesterol sphingomyelin within planar rafts and caveolae. The aim is to describe their evolution under treatment, which could lead to interventional studies.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Blood sample | |
| OTHER | Retinal photography: | |
| OTHER | dialyse |
Timeline
- Start date
- 2014-04-17
- Primary completion
- 2017-06-30
- Completion
- 2017-06-30
- First posted
- 2016-08-05
- Last updated
- 2019-05-03
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02857556. Inclusion in this directory is not an endorsement.