NCT02855645

The Effects of Trichosanthes Root on Blood Sugar in Patients With Diabetes Mellitus

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: China Medical University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Diabetes mellitus (DM) locates fifth of ten leading death etiology, the population of diabetic patients has a tendency of increase. Trichosanthes root is called as Tian Hua Fen, According to traditional Chinese writing record that Trichosanthes root has the action of downbear fire, moisten dryness, and slippery phlegm, and release thirst. The Trichosanthes root may lower blood sugar levels in the modern study. The investigators designed a double blind, randomized controlled study, a total of 60 diabetic patients with high blood sugar were divided into treatment and control groups, and each group was 30 patients. In the treatment group, oral administration of Trichosanthes root 1.5 g, bid/day for 84 days continuously; in the control group, oral administration of Trichosanthes root placebo 1.5 g, bid/day for 84 days continuously. The main outcome measure was the changes of plasma blood sugar and Glycated hemoglobin A1c (HbA1c) levels changed before and after Trichosanthes root treatment. The investigators predict the results of the present study indicated that Trichosanthes root can improve plasma blood sugar and glycated hemoglobin A1c levels.

Conditions

• Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	Trichosanthes root	Trichosanthes root at a rate of 1.5 g two times per day for 84 days.
DRUG	Placebo	Trichosanthes root at a rate of 0.15g (10%) two times per day for 84 days.

Timeline

• Start date: 2016-07-01
• Primary completion: 2017-04-01
• First posted: 2016-08-04
• Last updated: 2016-11-16

Locations

1 site across 1 country: Taiwan