NCT02849561

Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest

Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest : Prospective Study of Routine Care

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 82 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

With the repercussion of 55 cases eachyear for 100 000 inhabitants in France, cardio respiratory arrest is a public health issue. The goal of this study is to evaluate the pupillary light reflex measured by the dimension of the pupil (diameter) as a prognosis factor neurological evolution in post cardiac arrest. By participating to this study, the patient get the same tratments and exams than in a usual managing cares. In addition of these events, the pupillary light reflex is studied as soon as the patient is accepted in the department, and then on the second day. Currently, the evaluation of the neurological becoming rely on a multimodal clinical and paraclinical approach. The study of the pupillary light reflex measured by the diameter of the pupil could be a prognosis factor of neurological evolution for patients in post cardiac arrest, so a reliable and available prognosis marker in patient care. The goal of this study is to evaluate the pupillary light reflex (RPM), measured by the diameter of the pupil as a prognosis factor of neurological evaluation of admitted patients after a cardiac arrest. Principal criteria of judgement is the percentage of the pupillary light reflex variation measured with Neurolight®, compared between two groups.

Conditions

• Cardio Respiratory Arrest

Interventions

Type	Name	Description
OTHER	Therapeutic hypothermia	With a mattress at 4°C to reach a central temperature at 33,5°C.
DEVICE	Synchronized Intermittent Mandatory Ventilation	Constant volume 6 ml/kg
OTHER	Electroencephalography
DEVICE	Pupillary light reflex surveillance	With Neurolight® device.
DEVICE	Transcranial Doppler	Monitoring tool for brain hemodynamic evaluation. With Philips HD15 Ultrasound system®.

Timeline

• Start date: 2014-01-01
• Primary completion: 2015-07-01
• Completion: 2015-07-01
• First posted: 2016-07-29
• Last updated: 2016-07-29

Locations

1 site across 1 country: France