NCT02849366

Combination of Cryosurgery and NK Immunotherapy for Recurrent Sarcoma

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Fuda Cancer Hospital, Guangzhou · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is the safety and efficacy of cryosurgery plus NK immunotherapy to recurrent sarcoma.

Detailed description

By enrolling patients with recurrent sarcoma adapted to enrolled criteria, this study will document for the first time the safety and the short and long term efficacy of the combined therapy using cryosurgery and natural killer (NK) cells. The safety will be evaluated by statistics of adverse reactions. The efficacy will be evaluated according to local relief degree, progress free survival (PFS) and overall survival (OS).

Conditions

• Recurrent Adult Soft Tissue Sarcoma

Interventions

Type	Name	Description
DEVICE	Cryosurgery	Percutaneous ablation under CT or ultrasound guidance
BIOLOGICAL	NK immunotherapy	Each treatment: 8-10 billion cells in all, transfuion in 3 times, i.v.

Timeline

• Start date: 2016-07-01
• Primary completion: 2017-07-01
• Completion: 2019-07-01
• First posted: 2016-07-29
• Last updated: 2019-09-12

Locations

1 site across 1 country: China