NCT02848703

Study " COFLORES "

Study " COFLORES ":Imaging of Coronary Reserve Without Tracers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 53 (actual)
• Sponsor: Assistance Publique Hopitaux De Marseille · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Myocardial perfusion is a major parameter characterizing the status of capillary circulation of the myocardium. Its quantification is possible using Magnetic Resonance Imaging (MRI) during the 1st pass of a contrast agent through the capillary system. This technique is radiation-free, but it is difficult to repeat measurements during a single exam. Also, a number of patients suffering from cardiac disease cannot receive contrast agent injections. The investigators have developed a totally non-invasive approach for quantifying myocardial perfusion. It is based on the magnetic labeling of arterial spins. Flowing into the capillaries (Arterial spin labeling, ASL). Goal : The major goal of this research protocol is to validate a totally non-invasive method of myocardial blood flow quantification using MRI without contrast agent injection

Conditions

• Myocardial Perfusion

Interventions

Type	Name	Description
DEVICE	Magnetic Resonance Imaging (MRI)
DEVICE	phosphorus-31 Magnetic Resonance Spectroscopy
DEVICE	sodium-23 MRI

Timeline

• Start date: 2016-07-26
• Primary completion: 2019-02-27
• Completion: 2022-10-27
• First posted: 2016-07-28
• Last updated: 2022-11-14

Locations

1 site across 1 country: France