Trials / Completed
CompletedNCT02847806
Effects of Replacement Therapy With Sexual Steroid Hormones on the Insulin Sensitivity of Hypogonadal Man
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 6 (actual)
- Sponsor
- University Hospital, Caen · Academic / Other
- Sex
- Male
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Sexual steroids administered to supra-physiological doses are likely to change the carbohydrate and lipid metabolism. Investigators propose to study in 12 hypogonadal men hypogonadotropic or hypergonadotropic treated with aromatase inhibitor, the respective effects of estradiol, testosterone or both steroids administered in a cross-over Latin squares plan on insulin sensitivity measured by the reference method of the hyperinsulinemic euglycemic clamp.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Estradiol (Insulin sensitivity) | |
| BIOLOGICAL | Testosterone (Insulin sensitivity) |
Timeline
- Start date
- 2008-01-01
- Primary completion
- 2015-12-01
- Completion
- 2016-08-01
- First posted
- 2016-07-28
- Last updated
- 2018-08-17
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02847806. Inclusion in this directory is not an endorsement.