NCT02847741

Predictive Nature of Total Cholesterol Threshold: Possible Link to Suicidal Behavior

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 555 (actual)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Suicidal behavior (SB) is a public health problem. The clinical model currently admitted to the understanding of SB is a stress vulnerability model, but so far, all scientific works has no clinical application. The management of psychiatric patients, including depressed subjects, faces the inability to detect those with a high risk of SB. Many studies have shown a link between low cholesterol and SB. A study has recently proposed a total cholesterol threshold below which the risk of suicide could be increased. However, a prospective study is needed to assess the predictive nature of such an indicator.

Detailed description

Investigators propose to assess, within a cohort of patients, the predictive value of a total cholesterol threshold in the occurrence of SB. 555 inpatients suffering from a current Major depressive disorder (MDD), hospitalized in the Department of Emergency Psychiatry and Post Acute Care will be recruited. Each patient will attend a total of 5 visits during a follow-up period of 18 months (visits at 1, 3, 6, 12, and 18 months)

Conditions

• Current Major Depressive Disorder

Interventions

Type	Name	Description
OTHER	patient's routine care	Interview by psychiatrists, questionnaires, blood analysis

Timeline

• Start date: 2012-06-01
• Primary completion: 2016-12-01
• Completion: 2017-04-01
• First posted: 2016-07-28
• Last updated: 2016-07-28

Locations

1 site across 1 country: France