NCT02845622

Effects of Hazelnuts and Cocoa on Metabolic Parameters and Vascular Reactivity

Effects of Hazelnuts and Cocoa on Metabolic Parameters and Vascular Reactivity in Healthy Subjects: A Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: Ospedale San Donato · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This study aims to assess the effects of hazelnuts, cocoa, and the combination of both on vascular reactivity and metabolic profile. Participants, divided in six groups, will receive one of these breakfast integrations for 14 days: group 1) 30 g peeled hazelnuts; group 2) 30 g unpeeled hazelnuts; group 3) snack with 30 g peeled hazelnuts; group 4) snack with 2.5 g cocoa powder; group 5) snack with 30 g peeled hazelnuts and 2.5 g cocoa; group 6) empty snack, control group.

Detailed description

In the last few years, the prevalence of overweight and obesity has increased in all age groups. The European Food Safety Authority stated "cocoa flavanols help maintain endothelium-dependent vasodilation, which contributes to normal blood flow". Several studies reported that a daily consumption of hazelnuts reduces the risk of cardiovascular disease. The hypothesis of this study is to demonstrate a beneficial effect of hazelnut and cocoa diet integrations on vascular reactivity and endocrine-metabolic parameters.

Conditions

• Cardiovascular Diseases
• Glucose Metabolism Disorders

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Hazelnut	This dietary supplement contains 30 g of hazelnut.
DIETARY_SUPPLEMENT	Cocoa	This dietary supplement contains 2.5 g of cocoa powder.
DIETARY_SUPPLEMENT	No hazelnuts / No cocoa	This dietary supplement does not contain hazelnut nor cocoa powder.
DIETARY_SUPPLEMENT	Cream	This dietary supplement is just a cream obtained by grinding hazelnuts.
DIETARY_SUPPLEMENT	Snack	This dietary supplement is a commercial snack containing either hazelnut or cocoa or both.

Timeline

• Start date: 2014-06-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2016-07-27
• Last updated: 2016-09-09

Locations

1 site across 1 country: Italy