Trials / Completed
CompletedNCT02844621
Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
Comparison of Gut Microbiota Composition and Systemic Inflammatory Markers Prior to and Post-Proton Pump Inhibitor Use in Older Adults
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 25 (actual)
- Sponsor
- The University of Texas Health Science Center at San Antonio · Academic / Other
- Sex
- All
- Age
- 60 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate the effects of a common over-the-counter medication, omeprazole, on the normal gut bacteria and inflammation in the body in healthy older adults.
Detailed description
This study aims to enroll 25 healthy subjects from San Antonio, Texas and the surrounding area. Study participants will be asked to provide a blood and stool sample at baseline, complete a 14-day course of omeprazole (Prilosec®), and then complete a follow-up blood and stool sample.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Omeprazole | 20mg orally once daily |
Timeline
- Start date
- 2016-05-01
- Primary completion
- 2016-12-01
- Completion
- 2016-12-01
- First posted
- 2016-07-26
- Last updated
- 2017-01-20
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02844621. Inclusion in this directory is not an endorsement.