NCT02844504

Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Kessler Foundation · Academic / Other
• Sex: Female
• Age: 40 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Breast cancer patients often suffer from long-term physical symptoms of weakness. In this study, investigators propose to compare how two different low intensity physical exercise training programs can improve handgrip strength for breast cancer patients with symptoms of weakness. Using brain imaging, the study will also investigate changes in brain structure, and muscle activity associated with handgrip.

Detailed description

Participants will be randomized to either a no treatment group or one of two low intensity 6-week exercise training. Outcomes will be measured at baseline, post-intervention and 4 weeks post intervention.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
BEHAVIORAL	Low Intensity Exercise Training 1	Subjects will perform handgrip exercise training at low intensity (20% maximal force) 5 times a week for 6 weeks (more details not provided to keep study blinded)
BEHAVIORAL	Low Intensity Exercise Training 2	Subjects will perform a different handgrip exercise training at low intensity (20% maximal force) 5 times a week for 6 weeks (more details not provided to keep study blinded)

Timeline

• Start date: 2016-05-01
• Primary completion: 2020-09-01
• Completion: 2020-09-01
• First posted: 2016-07-26
• Last updated: 2020-10-05

Locations

2 sites across 1 country: United States