Trials / Unknown
UnknownNCT02841423
Postoperative Cognitive Dysfunction After Propofol Anesthesia for Noncardiac Surgery
Postoperative Cognitive Dysfunction After Intravenous Anesthesia or Closed-loop Coadministration of Propofol and Remifentanil Guided by Bispectral Index for Noncardiac Surgery : a Randomized Monocenter Study
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 204 (estimated)
- Sponsor
- Centre Hospitalier Universitaire de Besancon · Academic / Other
- Sex
- All
- Age
- 55 Years
- Healthy volunteers
- Not accepted
Summary
Background: Postoperative cognitive dysfunction (POCD) in elderly patients after noncardiac surgery is a common problem. Therefore,this study was designed to assess POCD after closed-loop coadministration of propofol and remifentanil guided by bispectral index in comparison to intravenous anesthesia in elderly patients undergoing major noncardiac surgery. Methods: After approval of the local ethical committee was obtained, 204 patients (American Society of Anesthesiologists physical status I-III; age, \> 55 yr) undergoing surgery (duration, \> 1 h) were enrolled into this pospective randomized monocenter study. Patients received anesthesia 3 days after using a neuropsychological test battery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | neuropsychological test battery |
Timeline
- Start date
- 2013-02-01
- Primary completion
- 2017-08-01
- Completion
- 2018-02-01
- First posted
- 2016-07-22
- Last updated
- 2016-08-05
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02841423. Inclusion in this directory is not an endorsement.