NCT02835404

Pelvic External Combined With 252-Cf Neutron Intracavitary Radiotherapy With or Without Platinum in Treating Advanced Cervical Cancer

A Randomized, Open Label, Single Centre Clinical Trial of Pelvic External Radiotherapy Combined With 252-Cf Neutron Intracavitary Brachytherapy With or Without Platinum in Treatment of Local Advanced Cervical Cancer

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study was to evaluate the efficacy and complication of the treatment of pelvic external combined with 252-Cf neutron intracavitary radiotherapy with or without platinum in local advanced cervical cancer patients in the short and long term.

Conditions

• Cervical Cancer
• Complications

Interventions

Type	Name	Description
DRUG	Nedaplatin	Chemotherapy: Nedaplatin(NDP) 30-40mg/m2 iv., on day1, 4weeks as one cycle
RADIATION	Pelvic External Radiotherapy	patients received 20 Gy2.0/f, for 25-27f (SSD)with 8mv-X rays (SSD)
RADIATION	252-Cf Neutron Intracavitary Brachytherapy	total dose of reference point A was 4400cGy, in four times Transvaginal implant sessions during Pelvic External Radiations

Timeline

• Start date: 2012-11-01
• Primary completion: 2017-06-01
• Completion: 2018-11-01
• First posted: 2016-07-18
• Last updated: 2016-07-18

Locations

1 site across 1 country: China