NCT02832843

Genome-Wide Association Study in Patients With Nontuberculous Mycobacterial Lung Disease

Elucidation of Genetic Susceptibility of Patients With Nontuberculous Mycobacterial Lung Disease Using Genome-Wide Association Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,808 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The aim of this study was to elucidate genetic susceptibility of patients with nontuberculous mycobacterial lung disease using genome-wide association study.

Detailed description

Nontuberculous mycobacteria (NTM) are ubiquitous environmental organisms. NTM lung disease is increasing, however, genetic susceptibility of patients with the disease have not been identified. To elucidate the genetic susceptibility of NTM lung disease, the investigators perform a genome-wide association study (GWAS) including patients with NTM lung disease and healthy controls (case : control = 1 : 3). The age-, sex-matched control group will be recruited from the Korean Healthy Twin Study.

Conditions

• Mycobacterium Infections, Nontuberculous

Timeline

• Start date: 2016-07-11
• Primary completion: 2017-11-20
• Completion: 2019-10-03
• First posted: 2016-07-14
• Last updated: 2019-12-13

Locations

1 site across 1 country: South Korea