NCT02832570

Sildenafil Efficacy Study on Time Walk From Peripheral Arterial Desease Patients (Stade II) With Arterial Claudication

Etude préliminaire Sur l'efficacité Aigue du Sildenafil Sur le Temps de Marche Chez Les Patients Atteints d'AOMI de Stade II présentant Une Claudication artérielle

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Efffect of a single dose oral intake of sildenafil Or placebo on the walking capacity on treadmill of PAD patients with claudication

Detailed description

Sildenafil 100mg or Placebo Oral intake 2 hours before the treadmill test Safety and security control throughout the period of drug efficacy (approx 4 hours) Evaluation of maximal walking distance for a constant load treadmill test (3.2 kml/h 10% slope)

Conditions

• Peripheral Arterial Occlusive Disease

Interventions

Type	Name	Description
DRUG	Sildenafil 100mg single oral dose	Measurement of maximal walking distance on a constant load treadmill test (3.12 km/ 10% slope)
DRUG	Placebo, Oral intake single dose	Measurement of maximal walking distance on a constant load treadmill test (3.12 km/ 10% slope)

Timeline

• Start date: 2016-11-07
• Primary completion: 2017-10-01
• Completion: 2017-10-01
• First posted: 2016-07-14
• Last updated: 2022-07-29