Trials / Completed
CompletedNCT02831907
Portal Flow Pulsatility as a Risk Factor for Acute Kidney Injury After Cardiac Surgery
Assessment of Portal Flow Using Bedside Doppler Ultrasonography for the Detection of Portal Pulsatility as a Risk Factor for Acute Kidney Injury in Cardiac Surgery Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 146 (actual)
- Sponsor
- Montreal Heart Institute · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the possible association between portal vein flow pulsatility and acute kidney injury after cardiac surgery. Participants will undergo assessment of portal vein flow and intra-renal blood flow using bedside Doppler ultrasound before surgery and daily for three days after cardiac surgery.
Detailed description
Acute kidney injury is a frequent complication after cardiac surgery. Venous congestion from right ventricular dysfunction and fluid overload can impair kidney perfusion resulting in the cardio-renal syndrome. An increase in the variation of blood flow velocity in the portal vein during the cardiac cycle called portal pulsatility is a sign of congestive heart failure. Portal pulsatility occurs when increased central venous pressure results liver venous congestion. The presence of abnormal portal pulsatility could be used as a marker of venous congestions in other organs such as the kidneys. Discontinuous intra-renal vein flow is a risk factor for death or re-hospitalization in heart failure patients and could be seen in patients with portal pulsatility.
Conditions
- C.Surgical Procedure; Cardiac
- Acute Kidney Injury
- Postoperative Complications
- Right-Sided Heart Failure
- Cardio-Renal Syndrome
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Cardiac surgery | All cardiac surgery procedures with the use of cardiopulmonary bypass |
Timeline
- Start date
- 2016-08-01
- Primary completion
- 2017-07-31
- Completion
- 2017-07-31
- First posted
- 2016-07-13
- Last updated
- 2017-08-30
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT02831907. Inclusion in this directory is not an endorsement.