Trials / Completed
CompletedNCT02823249
Effect of Amino Acids and Sugar Alcohols on Satiation Peptides and Activation of Specific Brain Regions
Effect of Amino Acids and Sugar Alcohols on Release of Satiation Peptides and Activation of Specific Brain Regions in Normal Weight and Obese Subjects
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- University Hospital, Basel, Switzerland · Academic / Other
- Sex
- All
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
With this study the investigators investigate the effects of amino acids (tryptophan, leucin) and sugar alcohols (xylitol, erythritol) on satiety mechanisms and brain activation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | 1.56 g L-Tryptophan | |
| DIETARY_SUPPLEMENT | 1.56 g L-Leucine | |
| DIETARY_SUPPLEMENT | 50 g Xylitol | |
| DIETARY_SUPPLEMENT | 75 g Erythritol | |
| DIETARY_SUPPLEMENT | 75 g Glucose | |
| DIETARY_SUPPLEMENT | Tap water | |
| DIETARY_SUPPLEMENT | Mixed liquid meal (Ensure Plus®; 17% protein, 29% fat and 54% carbohydrate) | |
| DEVICE | Nasogastric Tube |
Timeline
- Start date
- 2014-05-01
- Primary completion
- 2015-04-01
- Completion
- 2015-04-01
- First posted
- 2016-07-06
- Last updated
- 2017-02-28
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT02823249. Inclusion in this directory is not an endorsement.