NCT02821169

Infiltration in the Region of the Palatine Ganglion Spheno by Ropivacaine on Postoperative Pain

Impact of Infiltration in the Region of the Palatine Ganglion Spheno by Ropivacaine on Postoperative Pain in the Setting of Endoscopic Sinonasal Surgery.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 184 (actual)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Endoscopic sinus surgery (ESS) is a prevalent surgical procedure. It is required in many chronic rhinosinusitis for whom the medical treatment failed. In order to improve the postoperative management of patients treated with ESS, we aim to assess the analgesic action of local injection of ropivacaine in the nasal fossa.

Detailed description

A prospective randomized double blind placebo controlled study was designed. Local injection of ropivacaine or placebo was conducted at the end of the surgical procedure in both nasal fossa through endoscopic view in the sphenopalatine region. Pain was measured in the postoperative course with visual analogic scale in the recovery room and the rhinologic department.

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	ropivacaine	injection of 4mL of ropivacaine in the sphenopalatine area through an endoscopic approach
DRUG	saline solution 0.9%	injection of 4 mL of saline solution in the sphenopalatine area through an endoscopic approach

Timeline

• Start date: 2015-04-01
• Primary completion: 2019-06-01
• Completion: 2019-06-01
• First posted: 2016-07-01
• Last updated: 2025-12-22

Locations

1 site across 1 country: France