NCT02808507

Comparative Effectiveness/Implementation of TB Case Finding in Rural South Africa

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 4,852 (actual)
• Sponsor: Johns Hopkins Bloomberg School of Public Health · Academic / Other
• Sex: All
• Age: 0 Years – 99 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare three strategies for finding TB cases in a rural Sub-Saharan African setting: 1) Screening all attendees of primary care clinics for TB; 2) Conducting household contact investigations of newly diagnosed TB cases; 3) Providing incentives to newly diagnosed TB cases and their contacts to promote contact screening for TB. For each intervention, investigators will measure comparative effectiveness in terms of cases identified as well as the cost-effectiveness and feasibility of implementation.

Conditions

• Tuberculosis

Interventions

Type	Name	Description
OTHER	Active TB case finding	Active TB case finding (ACF) refers to any number of strategies used to identify individuals with active TB disease, outside of passive case finding. In passive case finding, individuals with symptoms present at health centers for diagnosis. In active case finding, the health system makes an effort to identify TB cases before they present passively.

Timeline

• Start date: 2016-07-18
• Primary completion: 2018-01-17
• Completion: 2020-01-30
• First posted: 2016-06-21
• Last updated: 2024-09-05
• Results posted: 2022-12-02

Locations

2 sites across 1 country: South Africa