NCT02806596

Bispectral Index to Guide Intubation in Pediatric Anesthesia

Use of Bispectral Index to Guide Intubation During Sevoflurane Anesthesia in Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of Liege · Academic / Other
• Sex: All
• Age: 2 Years – 8 Years
• Healthy volunteers: Accepted

Summary

This prospective study aimed to determine the minimal level of Bispectral index needed for quality laryngoscopy before ear, nose and throat surgery in children.

Detailed description

* Children will received intra-rectal premedication based on midazolam 0.4mg * Children will be monitored according to standard guidelines * One blinded anesthesiologist will be in charge of anesthesia induction and the other one will be in charge of data collection (end tidal sevoflurane concentration, sevoflurane minimal alveolar concentration, bispectral index) and guidance of induction according to the predetermined bispectral index (up and down allocation)

Conditions

• Anesthesia

Interventions

Type	Name	Description
DRUG	Sevoflurane	After at least 4 minutes of stable inspired sevoflurane concentration, that concentration will be titrated to obtain a targeted bispectral index (BIS) level required for perform laryngoscopy. This level was initially set at 40, based on a preliminary study showing that such level of BIS was obtained at the laryngoscopy after common general anesthesia induction. For the next patients, BIS target was set according to a sequential allocation method (up and down).

Timeline

• Start date: 2010-01-01
• Primary completion: 2013-06-01
• Completion: 2013-06-01
• First posted: 2016-06-20
• Last updated: 2016-06-29