NCT02805036

Comparison of the Hemodynamic Safety of Two Common Alveolar Recruitment Manoeuvres With Regard to Cardiac Output in a Surgical Intensive Care Unit

Comparison of the Hemodynamic Safety of Two Common Alveolar Recruitment Manoeuvres With Regard to Cardiac Output in a Surgical Intensive Care Unit: a Randomized Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Protective ventilation - combining a low tidal volume (between 6 and 8 ml/kg) and alveolar recruitment (AR) manoeuvres repeated every 30 minutes - is currently the standard of care for decreasing morbidity associated with mechanical ventilation. In contrast, there is no consensus on the type of recruitment manoeuvre, which varies from one centre to another and from one study to another. The investigators intend to compare two currently used AR techniques with regard to their ventilatory efficacy and hemodynamic safety: * An end-tidal plateau at 30 cmH20 for 30 seconds. * An end-tidal plateau at 10 cmH20 above the patient's plateau pressure for 30 seconds, without exceeding 30 cmH20.

Conditions

• Positive-Pressure Respiration

Interventions

Type	Name	Description
DEVICE	echocardiography	• Prospective, simultaneous recording of the cardiac output (measured non-invasively via transthoracic echocardiography) and a number of parameters commonly monitored in the surgical intensive care unit (CVP, SBP/DBP/MBP).
DEVICE	Arterial oximetry	measured by co-oximetry of a blood sample taken via the arterial catheter implemented for critical care

Timeline

• Start date: 2015-11-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2016-06-17
• Last updated: 2017-02-23

Locations

1 site across 1 country: France