Clinical Trials Directory

Trials / Completed

CompletedNCT02802930

Test the Phototoxicity of Sunscreen Products

A Randomized Study to Assess the Potential for Phototoxicity of SPF 50 Y65 110, SPF 50 Y51 002 and SPF 15 V27-104 in Human Subjects

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
32 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study was to evaluate the potential for phototoxicity of the sun care products SPF 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 compared to that of a negative control (0.9% sodium chloride \[NaCl\]) after a single 24 h application of test materials followed by irradiation with ultraviolet A (UVA) and ultraviolet B (UVB). The secondary objective of this study was to evaluate the safety of the sun care products SPF 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 combined with UVA/B irradiation by monitoring adverse events (AEs) throughout the study.

Conditions

Interventions

TypeNameDescription
DRUGSPF 50 Y65 110 (BAY987519)Application of 200 µL in an occlusive patch of Webril (0.150 ± 0.010 mg) compared to that of a negative control (0.9% sodium chloride, NaCl) and followed by irradiation with UV A and UVB.
DRUGSPF 50 Y51 002 (BAY987519)Application of 200 µL in an occlusive patch of Webril compared to that of a negative control (0.9% sodium chloride, NaCl) and followed by irradiation with UV A and UVB.
DRUGSPF 15 V27 104 (BAY987519)Application of 200 µL in an occlusive patch of Webril compared to that of a negative control (0.9% sodium chloride, NaCl) and followed by irradiation with UV A and UVB.
DRUGSodium chloride [NaCl]Negative control (200 µL, 0.9% sodium chloride \[NaCl\]) after a single 24 h application of test materials followed by irradiation with ultraviolet A (UVA) and ultraviolet B (UVB).

Timeline

Start date
2015-04-20
Primary completion
2015-04-26
Completion
2015-04-26
First posted
2016-06-16
Last updated
2018-12-12

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02802930. Inclusion in this directory is not an endorsement.