NCT02801539

Respiratory Muscle Training in L-Onset Pompe Disease (LOPD)

Respiratory Muscle Training in Late-Onset Pompe Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is being done to test the effects of respiratory muscle training (RMT) in patients with late-onset Pompe Disease (LOPD) who have weakness of their breathing muscles. The results of this study will help design future research studies about RMT in LOPD. The goals of this study are to decide if sham-RMT is a useful control condition for RMT and to choose the best ways to measure the health benefits of RMT in LOPD.

Conditions

• Glycogen Storage Disease Type II

Interventions

Type	Name	Description
DEVICE	RMT therapy using modified RMT device	The exercises provided by the RMT device is intended to strengthen breathing muscles.
DEVICE	Sham-RMT therapy using modified RMT device	The exercises provided by the Sham-RMT modified device is not intended to strengthen breathing muscles.

Timeline

• Start date: 2017-02-02
• Primary completion: 2018-10-22
• Completion: 2019-04-17
• First posted: 2016-06-16
• Last updated: 2019-07-30

Locations

1 site across 1 country: United States