NCT02800772

Impact of Intraduodenal Acetic Acid Infusion on Pancreatic Duct Cannulation During Endoscopic Retrograde Cholangiopancreatography: a Double-blind, Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 210 (actual)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Intraduodenal acetic acid can stimulate secretion of water and bicarbonate from pancreatic ductal cells. In this study, acetic acid spraying to duodenal bulb was compared with saline solution for the facilitation of pancreatic duct cannulation in patients.The primary outcome was successful deep pancreatic duct cannulation. The secondary outcomes were the appearance of the major and minor papillary orifice, pancreatic juice flow from the papilla, time to achieve deep pancreatic duct cannulation, and fluoroscopy time for deep pancreatic duct cannulation in the acetic acid group versus saline group.

Conditions

• Pancreatic Duct Cannulation During Endoscopic Retrograde Choledochopancreatography

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	acetic acid
DIETARY_SUPPLEMENT	saline

Timeline

• Start date: 2016-06-01
• Primary completion: 2017-08-01
• Completion: 2017-10-01
• First posted: 2016-06-15
• Last updated: 2017-11-17

Locations

1 site across 1 country: China