Clinical Trials Directory

Trials / Completed

CompletedNCT02797821

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

A Phase 2a, Randomized, Multicenter, Open-Label, Pharmacokinetic, and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
27 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study was to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of asfotase alfa in adult participants with pediatric-onset HPP.

Conditions

Interventions

TypeNameDescription
DRUGAsfotase alfa

Timeline

Start date
2016-06-06
Primary completion
2017-06-21
Completion
2017-06-21
First posted
2016-06-14
Last updated
2019-09-17
Results posted
2018-07-10

Locations

4 sites across 2 countries: United States, Germany

Source: ClinicalTrials.gov record NCT02797821. Inclusion in this directory is not an endorsement.