NCT02797028

Investigation of the Atherogenic Effects of Uric Acid-modified in Endothelial Dysfunction and the the Preventional Mechanism by Anthocyanidines

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 320 (estimated)
• Sponsor: Guangzhou General Hospital of Guangzhou Military Command · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to confirm the protective effect and mechanism of anthocyanins on hyperuricemia patients with Cardiovascular disease.

Detailed description

Hyperuricemia patients who have the ability to complete the intervention study in the early stage of study were selected as the research subjects. A randomized controlled double blind control method was used to study the effect of one year of anthocyanins intervention. Serum UA levels, oxidative stress, AGEs, and endothelial function are detecting in patients with hyperuricemia who were treated with anthocyanins and placebo. Providing scientific basis of anthocyanins for the treatment with hyperuricemia and delaying atherosclerosis.

Conditions

• Cardiovascular Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Anthocyanidins capsule	Continuous intervention for 1 years, detect the indicators in the intervention of 0,6,12 months
DIETARY_SUPPLEMENT	Placebo capsule	Continuous intervention for 1 years, detect the indicators in the intervention of 0,6,12 months
DRUG	Allopurinol	Continuous intervention for 1 years, detect the indicators in the intervention of 0,6,12 months

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-10-01
• Completion: 2017-12-01
• First posted: 2016-06-13
• Last updated: 2016-06-13

Locations

1 site across 1 country: China