Trials / Completed
CompletedNCT02796924
Treating Non-epileptic Seizures Using Magnetic Brain Stimulation
The Efficacy of Transcranial Magnetic Stimulation in the Treatment of Non-epileptic Seizures
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- University of Manitoba · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) - a form of non-invasive brain stimulation - to decrease the frequency of psychogenic non-epileptic seizure (PNES) episodes in patients with PNES.
Detailed description
This study is an open label pilot study that aims to recruit 15 individuals with diagnosed PNES to investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) to decreasing the frequency of psychogenic non-epileptic seizure (PNES) episodes. rTMS is a non-invasive method of brain stimulation that uses rapid magnetic pulses applied over the scalp to active neurons in a specified target location of the brain. Electronic as well as paper-and-pencil questionnaires will be used to asses patient's psychiatric symptoms and functional impairment both before and after treatment to monitor symptom-changes.Treatment will consist of daily sessions of high frequency (20 Hz) rTMS applied over the right temporoparietal junction (TPJ) of the cerebral cortex. Patients will receive two sessions per day for 15 consecutive weekdays. Each session will take approximately 20 minutes to complete. Results of the questionnaires will be analyzed to determine the effect of the treatment on PNES episodes and functional impairment. As a pilot study, this research will be used to evaluate the effect size and the feasibility of a more definitive project in the future. Both patient response and tolerability to rTMS will be analyzed.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | MagStim Rapid2 Transcranial Magnetic Simulation | A non-invasive method of brain stimulation |
Timeline
- Start date
- 2016-06-01
- Primary completion
- 2019-04-01
- Completion
- 2019-09-01
- First posted
- 2016-06-13
- Last updated
- 2020-09-30
- Results posted
- 2020-09-30
Source: ClinicalTrials.gov record NCT02796924. Inclusion in this directory is not an endorsement.