NCT02795208

Lung Recruitment Improves Right Ventricle Performance

Lung Recruitment Improves Right Ventricle Performance After Cardio-Pulmonary Bypass

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Hospital Privado de Cordoba, Argentina · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study test whether a lung recruitment maneuver improves the right ventricle performance after cardiopulmonary bypass. Half of the patients received an standard protective ventilation and the other half the same ventilatory pattern after a lung recruitment maneuver.

Detailed description

Atelectasis is developed in 90% of anesthetized patients after surgery. Protective ventilation with low tidal volumes and positive-end expiratory pressure (PEEP) promotes atelectasis with the potential right ventricle dysfunction induced by the increment in afterload (activation of the pulmonary hypoxic vasocontriction reflex). Lung recruitment can improve the right ventricle performance caused by atelectasis because the pulmonary hypoxic vasocontriction reflex desapear in a normal aerated lungs.

Conditions

• Atelectasis

Interventions

Type	Name	Description
PROCEDURE	Lung recruitment maneuver	The lung recruitment maneuver consists in a brief and controlled increment in airways pressure (20 cmH2O of PEEP + 20 cmH2O of driving pressure) for 10 breaths.

Timeline

• Start date: 2015-03-01
• Primary completion: 2016-03-01
• Completion: 2016-04-01
• First posted: 2016-06-10
• Last updated: 2016-06-14