NCT02791178

Optical Coherence Tomography in STEMI

Plaque Evaluation by Optical Coherence Tomography and Its Association With Microvascular Obstruction in Reperfused STEMI Patients - The POMS Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 35 (estimated)
• Sponsor: National Heart Centre Singapore · Academic / Other
• Sex: All
• Age: 21 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The overall objective of this research proposal is to use OCT to investigate those morphological culprit plaque characteristics associated with the risk of developing MVO in reperfused STEMI patients.

Detailed description

The specific research objectives include: 1. To use OCT to determine the type of plaque (plaque rupture, plaque erosion or calcified nodule) most associated with the presence and severity of MVO (as measured by IMR and cardiac MRI). 2. To use OCT to investigate the relationship between the extent of tissue protrusion and the amount of residual stent thrombus with the presence and severity of MVO (as measured by IMR and cardiac MRI).

Conditions

• STEMI

Interventions

Type	Name	Description
PROCEDURE	Optical coherence tomography (OCT)	Special camera to study part of your heart that was affected
PROCEDURE	Index of microcirculatory resistance (IMR)	Special wire to study part of your heart that was affected
OTHER	Cardiac MRI	Special scanner if the heart to assess the damage of your heart

Timeline

• Start date: 2016-02-01
• Primary completion: 2018-01-01
• Completion: 2018-01-01
• First posted: 2016-06-06
• Last updated: 2016-06-06

Locations

1 site across 1 country: Singapore