Trials / Completed
CompletedNCT02782078
Pharmacological Interaction of Rifampicin on Clindamycin in Staphylococcic Osteoarticular Infections
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Clindamycin and rifampicin are authorized in osteoarticular infection treatment (IDSA guidelines) but some interaction is observed. The objective of this study is to evaluate and quantify rifampicin interaction on clindamycin
Detailed description
It could suggest modification of recommended doses or incitement to antibiotic dosage. Thus, theses antibiotics, if association is allowed, could limit fluoroquinolones prescription and avoid some antibiotic resistance.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Clindamycin and rifampicin dosages | blood samples for clindamycin and rifampicin dosages (for each patient) |
Timeline
- Start date
- 2017-03-06
- Primary completion
- 2018-12-12
- Completion
- 2019-01-03
- First posted
- 2016-05-25
- Last updated
- 2020-03-27
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02782078. Inclusion in this directory is not an endorsement.